Fecha de publicación: -- Fuente: PubMed "rice" Plant Physiol Biochem. 2026 Nov 7;240:111946. doi: 10.1016/j.plaphy.2026.111946. Online ahead of print.ABSTRACTAbiotic stresses such as drought, salinity, heavy metals, heat, and cold disrupt cellular redox homeostasis, resulting in the excessive production of reactive oxygen species (ROS) and oxidative damage that negatively affect plant growth and productivity. Under controlled conditions, lower level of ROS act as signaling molecule, whereas, at elevated levels with biotic and abiotic stress factors, causes cellular damage. This review critically examines the molecular mechanisms involved in redox homeostasis in plants, including both enzymatic and non-enzymatic antioxidant systems. The integrated roles of phytohormone signaling and plant growth-promoting bacteria (PGPB) in regulating ROS metabolism, boosting antioxidant capacity, and enhancing abiotic stress tolerance are further discussed. Mechanistic insights into plant stress adaptation are provided by evaluating recent advances in transcriptional regulation, epigenetic modification, and redox-associated regulatory networks. Moreover, we review the contributions of multi-omics approaches toward understanding redox regulation and identifying key molecular components involved in stress resilience. Finally, emerging applications of synthetic biology and artificial intelligence are explored as potential tools for engineering redox regulatory networks to accelerate the development of climate-resilient crops. Overall, this review provides an integrated mechanistic framework outlining how redox biology, PGPB interactions, and next-generation engineering strategies can be combined to enhance crop resilience and sustainable agricultural productivity under future environmental shifts.PMID:43000026 | DOI:10.1016/j.plaphy.2026.111946