Fuente: PubMed "rice" Chem. 2025 May 8;11(5):102573. doi: 10.1016/j.chempr.2025.102573.ABSTRACTThe biosynthesis of bioorthogonal chemical handles for precise protein labeling remains a significant challenge. In this issue, Thomas Huber and colleagues report the successful biosynthesis of nitrile-containing amino acids and their site-specific incorporation into proteins, enabling efficient protein conjugation and fluorogenic labeling.PMID:42006091 | PMC:PMC13089989 | DOI:10.1016/j.chempr.2025.102573