Propolis as a Key Source of p-Coumaric Acid Permeating Honey and Sucrose Syrup Stores of Honey Bees

Fuente: PubMed "bee pollen"
Insects. 2025 Nov 13;16(11):1159. doi: 10.3390/insects16111159.ABSTRACTThe natural phenolic compound p-coumaric acid supports honey bee health by enhancing detoxification, immunity and longevity. It also possesses antioxidant, anti-inflammatory and anticancer properties relevant to human health. While commonly detected in honey and pollen, it is absent from nectar and sucrose-based supplements typically used in beekeeping. Concerns have been raised whether supplemental saccharide feeding deprives bees of this essential phytochemical. In this study, we quantified p-coumaric acid in various bee-derived products and in supplementary sucrose syrup before and after feeding to bees, using HPLC-HRMS analysis. Although fresh sucrose syrup contained negligible amounts of p-coumaric acid, syrup stored in capped combs exhibited levels comparable to or higher than those in honey. We identified propolis in combs as the primary source of p-coumaric acid, diffusing into both honey and sucrose syrup during storage. Our findings demonstrate that supplemental feeding with sucrose syrup does not diminish the bees' access to this key phytochemical and underscore the importance of a propolis-rich environment in bee health management.PMID:41302906 | PMC:PMC12653071 | DOI:10.3390/insects16111159