Fecha de publicación: 06/10/2021 Fuente: WIPO "pollen" The present invention discloses a substance for treating and/or preventing allergic diseases and a design method and preparation method thereof. The stable structure corresponding to the substance related to the allergic disease is used as the substance for treating and/or preventing the allergic disease. The essence of disease is the imbalance of biological structure system. The imbalance of the structure of the substance in the biological structure system will cause diseases related to said substance. The present disclosure relates to the treatment and/or prevention of the allergic disease by recognizing the stable structure corresponding to the substance by the body, adjusting the expression of its gene expression or genes by the self-adaptation, self-organization and other functions of body's structural system, and restoring the balance of the structure of the substance in the biological structure system.