Fecha de publicación: 22/11/2019 Fuente: WIPO "royal jelly" The invention discloses a preparation method of high-hydrophilicity solid royal jelly, comprising the following steps: heating royal jelly raw stock, filtering to remove impurities to obtain a royal jelly stock solution, adding a conditioning agent into the royal jelly stock solution to form liquid royal jelly, homogenizing to regulate the viscosity of the liquid royal jelly, adding the liquid royal jelly into an electrostatic spinning device, setting working parameters of the electrostatic spinning device, and performing electrostatic spinning to obtain the high-hydrophilicity solid royal jelly. After the royal jelly is nanocrystallized, the specific surface area of solids is increased, the surface hydrophobic effect of the royal jelly is reduced, and the dissolution degree of the royal jelly is increased. By adopting the process step of adding hydroxypropyl-beta-cyclodextrin and sodium chloride, the operability of homogenization is achieved, and the solubilizing ability of insolublecomponents of the royal jelly is improved.