Fecha de publicación: 21/09/2018 Fuente: WIPO "royal jelly" ABSTRACT:The  activity  of  senescence  associated  enzymes,  particularly  senescence  associated  beta-galactosidase (SA-β-gal) is detrimental to skin health. Such enzymes cause a host of deleterious effects such as premature aging, DNA damage, protein oxidation, production of reactive oxygen species, etc. The present disclosure provides a composition comprising xanthohumol, chrysin, and royal jelly peptide, which at particular w/w ratios, ameliorates the effect of senescence   associated enzymes in dermal cells.