A patch for at least partially reducing at least one of pain, swelling, inflammation and irritation in at least one body part of a user is provided. The patch includes at least one cloth layer having the propolis composition embedded therein. The patch includes a first plastic layer disposed immediately against a first side of the at least one cloth layer, and a second plastic layer disposed immediately against a second side of the at least one cloth layer opposite the first side, such that the at least one cloth layer is sandwiched between the first and second plastic layers. The propolis composition is configured to at least partially reduce at least one of perceived pain, swelling, inflammation and irritation when the patch is applied to the at least one body part. Related methods of use and/or manufacture for such a patch are also provided.