Fecha de publicación: 07/01/2009 Fuente: WIPO "bee" Metformin may be used in the treatment of diseases or condiitons with raised serum amyloid A levels, in particular secondary amyloidosis and associated diseases (rheumatoid arthritis, systemic lupus erythematosus, Reiter's syndrome, ankylosing spondylitis, Sjogren's syndrome, osteomyelitis, tuberculosis). Metformin may be used in conjunction with a 2ndcompound (e.g. an aldose reductase inhibitor, a glycogen phosphorylase inhibitor and other compounds as per claim 2).