METHODS FOR IDENTIFYING COMPOUNDS THAT DIRECTLY BIND TO INSECT TRANSIENT RECEPTOR POTENTIAL CHANNELS

Fecha de publicación: 25/04/2018
Fuente: WIPO "apis mellifera"
The present invention relates to a screening method for determining whether or not a candidate compound directly binds to an insect transient receptor potential V (TRPV) channel. The present invention further provides a method of identifying a compound that directly binds to a Nanchung protein, TRP and/or TRPV protein and/or channel using a binding assay. The present invention further provides a method of classifying an insecticide compound by its mode of action using the binding assay and/or a functional assays.