Chimeric retinoid X receptors and their use in a novel ecdysone receptor-based inducible gene expression system

Fecha de publicación: 12/10/2011
Fuente: WIPO "apis mellifera"
This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to a novel ecdysone receptor/chimeric retinoid X receptor-based inducible gene expression system and methods of modulating gene expression in a host cell for applications such as gene therapy, large-scale production of proteins and antibodies, cell-based high throughput screening assays, functional genomics and regulation of traits in transgenic organisms.