Methods, apparatus, systems and articles of manufacture manage credentials in hyper-converged infrastructure s are disclosed. An example method includes establishing, by executing an instruction with at least one processor, a communication between a software defined data center manager of the hyper-converged infrastructure and a component of the hyper-converged infrastructure using first credentials included in a known hosts file. The example method also includes generating, by executing an instruction with the at least one processor, second credentials at the component in response to a power-on event detected by the software defined data center manager. The example method also includes recording, by executing an instruction with the at least one processor, the second credentials at the known host file.