Fecha de publicación: 01/10/2008 Fuente: WIPO "miel" Use of lipid A (I) of Vitreoscilla filiformis comprising tetrahydro-pyran compound (X), for the preparation of a composition to inhibit the proliferation of microbial flora, preferably undesirable skin bacteria, to prevent and/or treat microbial infections and superinfections of the skin, and to prevent the microbial proliferation in cell or organotypic culture, is claimed. Use of lipid A (I) of Vitreoscilla filiformis comprising tetrahydro-pyran compound of formula (X); when R is (PO(OH)2) group, (I) comprises its inorganic salt, a primary, secondary or tertiary amine salt, or a phosphoethanolamine salt, for the preparation of a composition to inhibit the proliferation of microbial flora, preferably undesirable skin bacteria, to prevent and/or treat microbial infections and superinfections of the skin, before, simultaneously or after using the peeling agent, and to prevent the microbial proliferation in cell or organotypic culture, is claimed. AG13-hydroxy decanoyl; AG23-dodecanoyloxy decanoyl; R : H or PO(OR1a)2; and R1a : H, 1-6C alkyl (optionally saturated), phenyl or benzyl ; An independent claim is included for a cosmetic process of skin peeling comprising simultaneously applying a peeling agent of the lipid A of Vitreoscilla filiformis. [Image] - ACTIVITY : Dermatological; Antiseborrheic; Vulnerary; Fungicide; Antiinflammatory; Virucide; Antiulcer; Antidiabetic; Antibacterial; Antimicrobial. - MECHANISM OF ACTION : None given.