A method includes storing data in a group of analog memory cells by writing respective analog values into the memory cells in the group. After storing the data, the analog values are read from the memory cells in the group one or more times using one or more respective read thresholds so as to produce readout results. Reliability measures are computed for the read analog values based on the readout results. An offset of the one or more read thresholds from an optimal read threshold position is estimated based on the reliability measures. The reliability measures are modified to compensate for the estimated offset, and the data stored in the analog memory cells in the group is decoded using the corrected reliability measures.