Fecha de publicación:
04/12/2020
Fuente: WIPO "miel"
The invention relates to a ruthenium-catalyzed alkylation reaction of cyclopropanol and sulfur ylide, and a series of 1, 5-diketone compounds can be synthesized by the method. According to the method,cyclopropanol is catalyzed by ruthenium to generate beta-carbon elimination ring opening, and safe, stable and easy-to-prepare sulfur ylide is used as a carbene precursor, so that the method has goodapplicability in the field of construction of 1, 5-diketone.