Recombinant adenovirus expressing two transgenes with a bidirectional promoter

Fecha de publicación: 20/10/2016
Fuente: WIPO "miel"
The invention provides recombinant adenovirus (rAd) and rAd vectors comprising a bidirectional mouse CMV (mCMV) promoter operably linked to a first transgene in one direction and to a second transgene in the opposite direction. The invention also provides methods of making and using such rAd and rAd vectors.