The invention relates to a carton for artificial multiplication and production of stingless bee honey for commercial use. The box is manufactured with plywood sandwich-type polypropylene-expanded polystyrene (EPS) and/or polyurethane (PUR) which allows thermoregulation to the interior thereof. The carton comprises a fixed front cover where a trap is placed to control pests whereby the stingless bees enter the breeding chamber. Also, it possesses a top coat and a removable rear wall which facilitates the inspection and harvesting of honey and pollen without destroying part of the system, as well as five wooden elements movable inside which enable a stable handling of the production and maintain the uniform temperature inside the box.