Fuente: PubMed "honey" Talanta. 2026 Jul 23;312(Pt A):130347. doi: 10.1016/j.talanta.2026.130347. Online ahead of print.ABSTRACTTetracycline hydrochloride (TCH) is a widely used antibiotic in animal husbandry and aquaculture practices, and its residual accumulation in food commodities constitutes a persistent public health concern. Therefore, sensitive, time-saving, and reliable analytical strategies for TCH are critical for guaranteeing food safety. Surface-enhanced Raman spectroscopy (SERS) has become an ideal analytical modality, attributed to its ultrahigh sensitivity, operational simplicity, and inherent molecular fingerprinting capability. The integration of plasmonic metal materials (PMPs) with the functional material provides a rational design strategy for advanced SERS substrates. A case in point is that of metal-organic frameworks (MOFs). However, the construction of MOF-PMPs composites is hindered by complex fabrication protocols, prolonged preparation time and high cost. Electrochemical deposition, characterized by rapid processing, facile parameter tuning, and environmental compatibility, presents a promising alternative for SERS substrate construction. In this work, we present a novel Ag/Zn-BTC@NF composite SERS substrate synthesized via two-step electrodeposition. The as-fabricated material delivers prominent SERS sensitivity. When R6G is used as the specific molecule, LOD (detection limit) can reach 10-9 M, and the enhancement factor is 6.6 × 106. Furthermore, the substrate achieved an LOD of 10-8 M for TCH and enabled its ingenious detection in milk and honey samples, with recoveries of 87.4 - 112.5%. The proposed methodology establishes an efficient and eco-friendly synthetic strategy for MOF-PMPs composites, thereby broadening the scope of SERS technology in food safety applications.PMID:42520631 | DOI:10.1016/j.talanta.2026.130347