Fecha de publicación: -- Fuente: PubMed "honey" J Food Sci. 2026 Nov;91(11):e71615. doi: 10.1111/1750-3841.71615.ABSTRACTOak honey is a type of honeydew honey that is in demand among consumers due to its remarkable functional properties. In this study, the individual phenolic profile and total phenolic content of oak honey samples collected from different locations in Türkiye, as well as their antioxidant and antimicrobial activities, were evaluated. Additionally, principal component analysis (PCA) was performed to observe similarities and differences among the obtained results. Analyses conducted using liquid chromatography-tandem mass spectrometry (LC-MS/MS) revealed that the total individual phenolic content of samples ranged between 12.84-41.81 µg/g. Among the 28 phenolics screened in samples, gallocatechin + epigallocatechin (0.206-17.536 µg/g), followed by gallic acid (1.884-5.369 µg/g) and pinobanksin (0.657-5.468 µg/g), were identified as the major phenolic compounds detected in the samples. Furthermore, the total phenolic content for the 21 honey samples examined in the study varied between 0.18-0.62 mg gallic acid equivalent (GAE)/g, with an average value detected as 0.42 mg GAE/g. Radical quenching activity results determined by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) test varied between 0.13-0.26 mg Trolox equivalent (TE)/g, with an average value identified as 0.21 mg TE/g. In antimicrobial activity assays, while oak honey samples prepared at a concentration of 80% (w/v) showed no inhibitory effect against Candida strains, they were observed to exhibit varying levels of inhibitory activity against Gram-positive and Gram-negative bacteria. The results revealed that, while samples obtained from the same phytogeographical region exhibited similarities in certain phenolic characteristics, they demonstrated significant differences in terms of phenolic profile and bioactive properties.PMID:42988776 | DOI:10.1111/1750-3841.71615