Fecha de publicación: 24/06/2021 Fuente: WIPO "tobacco agriculture" The present disclosure provides materials and methods relating to transgenic plants. In particular, the present disclosure provides novel nucleic acid molecules, constructs, and methods for generating transgenic plants (e.g., tobacco plants) with modifications involving Production of Anthocyanin Pigment 1 (PAP1) and Transparent Testa 8 (TT8), as well as Nicotiana tabacum JAZ1, JAZ3, JAZ7, and JAZ10. Transgenic plants having such modifications exhibit enhanced characteristics such as reduced levels of alkaloids and nitrosamine carcinogens.