Fuente: WIPO "tobacco agriculture" The invention relates to an indicator stenotrophomonas strain 107E3 as well as application, a product and a method thereof, belonging to the technical field of microorganisms. The invention provides an indicator stenotrophomonas indicatrix strain 107E3, and the preservation number of the indicator stenotrophomonas indicatrix strain 107E3 is CCTCC (China Center for Type Culture Collection) No: M 2019923. The invention also provides an application of the indicator stenotrophomonas indicatrix strain 107E3 in the aspect of preventing and treating bacterial wilt, and the invention also provides an application of the indicator stenotrophomonas indicatrix strain 107E3 in the aspect of preventing and treating bacterial wilt. The invention further provides a microbial agent based on the indicator stenotrophomonas indericatrix strain 107E3, and a method for preventing and treating the bacterial wilt. The invention further provides a bacterial agent based on the indicator stenotrophomonas indericatrix strain 107E3 and a method for preventing and treating the bacterial wilt. Experiments prove that an indicator, namely the stenotrophomonas indicatrix strain 107E3, can be used for effectively maintaining the disease index of a tobacco plant suffering from bacterial wilt at a relatively low level.