Fuente: PubMed "Tomato process" Naunyn Schmiedebergs Arch Pharmacol. 2026 Jun 1. doi: 10.1007/s00210-026-05487-3. Online ahead of print.ABSTRACTThe development of efficient and sustainable antibacterial agents is crucial to address the growing threat of multidrug-resistant pathogens. In this study, we report the synthesis and characterization of a novel nanocomposite selenium-doped titanium dioxide supported on functionalized carbon nanotubes (Se-TiO2@CNTs) with enhanced photocatalytic antibacterial performance under visible light. This new material was synthesized through the sol-gel method by in situ Se-TiO2@CNTs nanocomposite decoration to achieve uniform dispersion and strong interfacial coupling between the components. Comprehensive characterization using XRD, TEM, SEM-EDS, FTIR, and UV-vis DLS confirmed successful Se doping of TiO2 and improved optical absorption in the visible range. The photocatalytic antibacterial activity was evaluated against Escherichia coli 90% and Ralstonia solanacearum, demonstrating the concentrations of 0.1 mg 82.98% bacterial inactivation within 24 h of visible-light irradiation. Mechanistic investigations revealed that the synergistic effects of Se doping facilitated efficient charge separation, suppressed electron-hole recombination, and boosted reactive oxygen species (ROS) generation, particularly •OH and •O2- radicals, leading to oxidative leakage of bacterial cell membranes and intracellular organelles. This work presents novel perspectives on the design of multifunctional modified Se-TiO2@CNTs nanocomposites exhibiting strong antibacterial activity against both animal and plant pathogenic bacteria. Specifically, it effectively inhibits E. coli (a representative animal pathogen) and Ralstonia solanacearum (a destructive plant pathogen), highlighting its potential as a dual-purpose antimicrobial agent in both medical and agricultural applications. These modified CNTs have limited applications in agriculture. We have synthesized these modified CNTs and applied them in both medical and agricultural applications.PMID:42219407 | DOI:10.1007/s00210-026-05487-3