CATIONIC SULFONAMIDE AMINO LIPIDS AND AMPHIPHILIC ZWITTERIONIC AMINO LIPIDS

Fuente: WIPO "tomato"
AABBSSTTRRAACCTT
The present disclosure provides one or more amino lipids such as an amino lipids containing a sullfonnicica acicdidor orsu sluflofnoieniacci adcidder diveartiivvaetiovfet ohef f thoremu floarsm:ulas:

wherein the variables are as defined herein. These amino lipids may be used in compositions with one or more helper lipids and a nucleic acid therapeutic agent. These compositions may be used to treat a disease or disorder such as cancer, cystic fibrosis, or other genetic diseases.