Fuente: WIPO "biotechnology" The invention relates to a synthetic or recombinant DNA sequence comprising a first DNA sequence which acts as a coding sequence for amino acid sequences of all, part, analogues, homologues, derivatives or combinations thereof of minactivin, a DNA sequence from whatever source obtained including natural, synthetic or semi-synthetic sources which hybridises to the first DNA sequence, a DNA sequence related by mutation, including single or multiple base substitutions, deletions, insertions and inversions, to the first DNA sequence or hybridising sequences or a DNA sequence which on expression codes for all, part, analogues, homologues, derivatives or combinations thereof of a polypeptide which is minactivin or which displays similary immunological or biological activity to minactivin. Also included are the minactivin protein, methods of its production, transformed hosts, oligonucleotide probes, antibody preparations against minactivin, cDNA sequences coding for minactivin and their preparation, compositions containing minactivin and its use...