Fuente: WIPO "biotechnology" A process is provided for producing recombinant albumin, the process comprising culturing a fungal cell expressing a recombinant albumin coding sequence and obtaining the albumin, wherein the cell has a genetic modification which causes the cell to have at least a reduced capacity of mannosylation of the recombinantly-expressed albumin and wherein the culture medium is at least 1,000L and is of pH 5.3 to 6.8. A process for the preparation of a highly pure albumin solution is disclosed, the process comprising subjecting albumin (preferably expressed and secreted by transformed yeast) to a series of chromatographic steps. A process for reducing the level of nickel in an albumin solution is also disclosed, as is a recombinant albumin coding sequence comprising two or more in-frame translation stop codons.