Fecha de publicación: -- Fuente: WIPO "biotechnology" The invention relates to a method of manufacturing of a lyophilized composition, which contains preparation of an antibacterial protein mixture, which has a destructive effect against such species: Staphylococcus arlettae, Staphylococcus aureus, Staphylococcus auricularis, Staphylococcus carnosus, Staphylococcus carprae, Staphylococcus chromogenes, Staphylococcus cohnii, Staphylococcus delphini, Staphylococcus epidermidis, Staphylococcus equorum, Staphylococcus gallinarum, Staphylococcus hemolyticus, Staphylococcus hominis, Staphylococcus intermedius, Staphylococcus kloosii, Staphylococcus lentus, Staphylococcus lugdunensis, Staphylococcus muscae, Staphylococcus pasteuri, Staphylococcus saprophyticus, Staphylococcus warneri, and Staphylococcus xylosus; preparation of the solution by mixing poloxamer 188, D-sorbitol, L-histidine, antibacterial protein mixture and subjecting the solution to lyophilization.