Fecha de publicación: -- Fuente: WIPO "biotechnology" The invention relates to microbiology and biotechnology. A method is proposed of complex processing of Saccharomyces yeast aimed at the better use of the components of starting material on the account of applied processing technologies and parameters of the process. A method includes acid hydrolysis of a yeast suspension, dividing the hydrolyzate obtaining a peptide and nucleotide extract and a protein residue, drying thereof, extracting the lipids from this residue by ethyl alcohol with the subsequent obtaining ergosterol from the lipids and also drying a nonfat protein residue. The yeast suspension is subjected to an alkali hydrolysis at pH=7.5-9.0, a temperature of 80 – 85 0C in the course of 30 - 40 minutes. The peptide and nucleotide extract obtained is subjected to thermo-alkali and thermo-acid hydrolyses obtaining a radioprotective extract with the subsequent neutralization and drying thereof.