Fuente: WIPO "biotechnology" The Arabidopsis NI16 gene was isolated in a yeast 2-hybrid screen via its interaction with the NIM1 protein. The NI16 gene encodes a protein involved in the regulation of SAR gene expression in plants. NI16 is strongly induced in NIM1-overexpressing plants treated with benzo(1,2,3)thiadiazole-7-carbothioic acid S-methyl ester (BTH). The NIMI interactor can be expressed in transgenic plants, either alone or in combination with the NIMI protein, to increase expression of SAR genes such as PR-1.