A splicing switch enables SR45a-driven thermotolerance in plants

Fuente: PubMed "industrial biotechnology"
Trends Cell Biol. 2026 Aug 20:S0962-8924(26)00157-1. doi: 10.1016/j.tcb.2026.08.001. Online ahead of print.ABSTRACTHeat stress reshapes plant transcriptomes through alternative splicing, yet the regulatory logic governing isoform switching remains poorly understood. Recently, a heat-activated, branch-point-dependent splicing switch in Serine/arginine-rich splicing factor 45a (SR45a) was uncovered by Xu et al. This switch couples transcriptional activation to isoform remodeling, driving thermotolerance.PMID:42624687 | DOI:10.1016/j.tcb.2026.08.001