Fecha de publicación: -- Fuente: PubMed "plant biotechnology" Free Radic Biol Med. 2026 Nov 9:S0891-5849(26)01266-9. doi: 10.1016/j.freeradbiomed.2026.11.015. Online ahead of print.ABSTRACTHydrogen peroxide (H2O2) plays a central role in cells, serving as important signal transduction molecule but also potentially causing oxidative stress, leading to cell death. Recent studies reveal that in addition to its many intracellular redox-driven signaling roles, H2O2 can mediate different cell-to-cell, organism-to-organism, and even interspecies communication, with major consequences for the health, symbiosis, and/or survival of the involved organisms. While new research has revealed some of the mechanisms and outcomes of interspecies H2O2 signaling, the effects of H2O2-driven interspecies communication routes on entire communities and ecosystems remain largely unknown. Here, we summarize current research on interspecies H2O2 signaling. We present examples from multiple biological systems to demonstrate the universality of H2O2/redox-driven communication mechanisms and discuss their effects on participating organisms. Finally, we highlight the potential contributions interspecies H2O2 signaling may have to communities and ecosystems and how studying interspecies H2O2 signaling can help us prevent long-term agricultural, ecological, and human health damages.PMID:43003155 | DOI:10.1016/j.freeradbiomed.2026.11.015