Fuente: PubMed "nature biotechnology" Osteoarthr Cartil Open. 2025 Nov 19;8(1):100706. doi: 10.1016/j.ocarto.2025.100706. eCollection 2026 Mar.ABSTRACTOBJECTIVE: To identify research priorities for osteoarthritis (OA) in Australia to reduce the individual and societal burden of OA.DESIGN: We used accepted priority setting methodology involving multiple stages: 1) gathering unanswered research priorities from selected literature; 2) assembling an expert panel and using an online survey to obtain additional priorities from panelists; 3) consolidating research priorities (eg. removing duplicates); 4) panel rating of priorities for importance on an 11-point numeric rating scale (0 ​= ​'not at all important; 10 ​= ​'extremely important') via another online survey; 5) analyzing and compiling the final list of priorities; and 6) addressing implementation via a one-day National Summit.RESULTS: 38 research priorities were identified from the literature. 288 nation-wide panel experts (204 consumers/carers/consumer organisations; 47 clinicians from 9 disciplines; 32 researchers; and 5 industry/research funders) provided an additional 99 priorities. Following consolidation, 90 priorities remained and were organised under 8 themes. 204 of the original panelists (71 ​%) rated the priorities. All priorities scored a mean importance rating ≥6 and so were retained, giving a final list of 90. Mean (SD) importance scores for the top 20 priorities ranged from 8.2 (1.9) to 8.9 (1.9). Overall, the top 3 priorities related to developing drugs/strategies to prevent disease progression and regeneration of damaged cartilage. There was variation across consumers, clinicians and researchers, with only 2 of the same priorities ranked in each of their top 20.CONCLUSIONS: We determined key research priorities for OA. These can help guide research directions and funding to enhance outcomes for people with OA.PMID:41399469 | PMC:PMC12701990 | DOI:10.1016/j.ocarto.2025.100706