Fuente: PubMed "nature biotechnology" Neuropathol Appl Neurobiol. 2026 Apr;52(2):e70071. doi: 10.1111/nan.70071.ABSTRACTMR-guided laser interstitial thermal therapy (LITT) offers a minimally invasive option for recurrent glioblastoma, but human post-treatment tissue data are scarce. In this case report, post-LITT tissue exhibited distinct zonal changes, including central necrosis within the ablation zone and reduced tumour proliferation with increased CD8+ T-cell infiltration in the perilesional transition zone, suggesting that LITT may influence the local immune landscape in recurrent glioblastoma.PMID:41912359 | DOI:10.1111/nan.70071