Fuente: PubMed "nature biotechnology" Nat Microbiol. 2026 Jun 19. doi: 10.1038/s41564-026-02408-1. Online ahead of print.ABSTRACTPrion and prion-like proteins are classically associated with protein misfolding, but amyloidogenic sequences can also participate in host defence. Here, using deep learning, we screened 19.3 million fragments from 2,897 curated prion-related proteins and identified 1,179 candidate antimicrobial peptides, which we term prionins. Among 75 synthesized prionins, 59 inhibited bacterial pathogens, 53 perturbed membranes and 2 reduced Acinetobacter baumannii infection burden in mice.PMID:42321536 | DOI:10.1038/s41564-026-02408-1