The influences of encapsulated essential oil and gallic acid on inflammation response, systemic immunity, gut health and performance in early weanling piglets

Fuente: PubMed "essential oil"
Res Vet Sci. 2026 Jul 9;210:106320. doi: 10.1016/j.rvsc.2026.106320. Online ahead of print.ABSTRACTThe study evaluated the influences of lemon grass essential oil (LGEO) and gallic acid (GA) supplementations on inflammation response, systemic immunity, gut health and performance in early weanling piglets. Thirty-two piglets were separated from parity-matched sows at the age of 3 weeks and randomly divided into four different supplementation groups: basal ration (control), LGEO, GA and LGEO + GA in basal diet. The inflammation response was monitored by measuring serum calprotectin level and neutrophil and lymphocyte ratio in blood, systemic immunity was evaluated by measuring serum immunoglobulin A (IgA) and immunoglobulin G (IgG), gut health was assessed by measuring amylase, lipase and ghrelin in serum, fecal microbial populations and diarrhea incidence and performance was evaluated on the basis of growth and mortality until day 21 post-weaning. The fecal Lactobacillus and Bifidobacterium counts were significantly increased in LGEO, GA and LGEO+GA groups while fecal coliform count was markedly dropped in LGEO and LGEO+GA groups. The GA supplementation markedly improved serum albumin and IgA concentrations, and attenuated calprotectin, ghrelin, globulin, amylase levels. The GA + LGEO supplementation significantly improved serum albumin level in early weanling piglets. Only one piglet died due to pneumonia in LGEO+GA group. In LGEO group, the diarrhea incidence was lowest among the supplementation groups and mean body weight was significantly higher on day 21 of weaning as compared to the control group. Taken together, it is concluded that the dietary supplementation of LGEO to early weaning pigs in a commercial swine production farm may be effective in improving growth performance and gut health.PMID:42424975 | DOI:10.1016/j.rvsc.2026.106320