Fuente: PubMed "essential oil" Biomed Res Int. 2026;2026(1):e5037275. doi: 10.1155/bmri/5037275.ABSTRACTBACKGROUND: Hair loss is a common condition with significant psychosocial impact. Although pharmacological treatments such as minoxidil are available, their long-term use may be associated with adverse effects. Plant-derived products are widely used in traditional medicine for hair care; however, scientific validation of their efficacy remains limited.OBJECTIVE: This study is aimed at evaluating the hair growth-promoting effects of a combination of Rosmarinus officinalis and Ricinus communis oils in a murine model.METHODOLOGY: Essential oil from R. officinalis was obtained by hydrodistillation, whereas fixed oil from R. communis seeds was extracted using Soxhlet extraction with hexane. Fifteen mice (n = 3 per group) were divided into five groups: rosemary oil, castor oil, combination (1 : 1), 2% minoxidil (positive control), and untreated (negative control). Treatments were applied topically once daily for 28 days. Hair growth was evaluated using hair length measurement, macroscopic observation, and standardized hair regrowth scoring. Data were analyzed using one-way ANOVA followed by Tukey's post hoc test. Statistical outputs are presented descriptively due to the small sample size and p values are reported for trend identification rather than inferential significance.RESULTS: The combination group showed higher mean hair length (12.88 ± 0.79 mm) compared with R. officinalis (12.68 ± 0.25 mm) and R. communis (10.10 ± 0.22 mm) and showed similar trends to 2% minoxidil (13.06 ± 0.21 mm). One-way ANOVA showed overall group differences. Statistical outputs are presented descriptively due to the small sample size; p values are reported for trend identification rather than inferential significance.CONCLUSION: The findings suggest that the combination of R. officinalis and R. communis oils may promote hair growth in a murine model. The present findings are derived from a murine model and cannot be directly extrapolated to human use.PMID:42112722 | DOI:10.1155/bmri/5037275