Fuente: PubMed "essential OR oil extract" Pregnancy Hypertens. 2026 Jun 21;45:101491. doi: 10.1016/j.preghy.2026.101491. Online ahead of print.ABSTRACTWhite-coat hypertension (WCH) during pregnancy has been linked to adverse maternal and fetal outcomes, although available evidence is inconsistent, particularly during the second half of gestation. This variability may be partly explained by heterogeneity in blood pressure (BP) phenotype definitions, especially regarding the inclusion of different ambulatory BP monitoring (ABPM) periods. We conducted a retrospective cohort study including pregnant women evaluated between 20 and 34 weeks of gestation within a high-risk pregnancy setting. Office BP and 24-h ABPM were obtained using a standardized protocol. BP phenotypes were classified as normotension, white-coat hypertension, masked hypertension, or sustained hypertension based on office BP and all ABPM periods (24-h, daytime, and nighttime). The primary outcome was a composite maternal endpoint including preeclampsia, eclampsia, or HELLP syndrome, while adverse fetal outcomes were also assessed. Logistic regression models were used to estimate adjusted odds ratios. Among 1415 women included, 56%(793) were normotensive, 2%(28) had WCH, 14.3%(203) masked hypertension, and 27.6% (391) sustained hypertension. The overall incidence of composite maternal outcome was 21.5%(304), with rates of 10.2%(81) in normotensive women, 7.1%(2) in those with WCH, 30.5%(62) in masked hypertension, and 40.7%(159) in sustained hypertension (p < 0.001). After adjustment, WCH was not associated with an increased risk of composite maternal outcome compared with normotension (OR 0.81; 95% CI 0.19-3.52). Adverse fetal outcomes were significantly more frequent in masked and sustained hypertension, but not in WCH. These findings suggest that when white-coat hypertension is defined using all ABPM periods, including nighttime BP, it may not be associated with a significantly increased maternal or fetal risk during the second half of pregnancy among women in a high-risk cohort. Accurate BP phenotype classification, particularly including nocturnal BP assessment, remains essential for appropriate risk stratification in pregnant women.PMID:42323930 | DOI:10.1016/j.preghy.2026.101491