Fecha de publicación: -- Fuente: PubMed "essential OR oil extract" APMIS. 2026 Nov;134(11):e70273. doi: 10.1111/apm.70273.ABSTRACTThe rising prevalence of antimicrobial resistance represents a major threat to public health and economic sustainability worldwide. In Europe, vancomycin-resistant Enterococcus faecium (VREfm) and carbapenemase-producing Enterobacteriaceae (CPE) are of particular concern, as they cause severe infections that are increasingly difficult or impossible to treat. Transmission of VREfm and CPE occurs predominantly in hospital settings, making prevention of nosocomial spread a central component of resistance control efforts. Effective containment relies on rapid detection of transmission events and early intervention to limit onward spread. This requires intensive laboratory surveillance capable of resolving both clonal transmission and horizontal gene transfer, supported by comprehensive sampling of clinical and environmental isolates. In addition, real-time sharing of isolate-level data between hospitals is essential to identify and manage cross-unit and inter-institutional transmission. Although such surveillance systems require sustained investment, their costs are modest compared with the substantial clinical and economic burden associated with infections caused by antibiotic-resistant bacteria. In this mini-review, we outline a strategy for preventing antimicrobial resistance, informed by its implementation in a large Danish healthcare region comprising six public hospitals.PMID:43003767 | DOI:10.1111/apm.70273