Fuente: WIPO "essential oil or extracts" Described are novel, supercritical CO2 essential oil extracts of Nigella sativa seeds, exhibiting positive entourage effects that function alone or synergistically in combination with other phytoceuticals or drugs to improve averse metabolic functioning and health. These compositions would be useful in the prevention, treatment or co-treatment of metabolic disorders such as obesity, hyperlipidemia, metabolic syndrome, diabetes, hepatic steatosis, and cardiovascular diseases.