A COMPOSITION COMPRISING THE PURIFIED ESSENTIAL OIL EXTRACT AND LOWER ALCOHOL SOLUBLE EXTRACT ISOLATED FROM ANGELICA GIGAS FOR THE PREVENTION AND TREATMENT OF NICOTINE ADDICTION AND WITHDRAWAL SYMPTOMS

Fuente: WIPO "essential oil or extracts"
The present invention is related to a composition comprising the purified essential oil extract and lower alcohol soluble extract isolated fromAngelica gigas Nakai for the prevention and treatment of nicotine addiction and withdrawal symptoms. The purified essential oil extract and lower alcohol soluble extract isolated fromAngelica gigas Nakaiof the present invention inhibits the sensitization effects on drug reinforcing property and decrease the behavior activity in nicotine drug addiction induced by chronic nicotine treatment by inhibiting the release of dopamine, DOPAC and HVC in a dose dependent manner. Therefore, it can be useful in treating or preventing nicotine addiction and withdrawal symptoms in the form of a medicine or health care food.