ISOLATED HONEY GLYCOPROTEIN FOR USE AS AN ANTIMICROBIAL AGENT

Fecha de publicación: 05/11/2015
Fuente: WIPO "royal jelly"
There is provided a composition comprising: an isolated glycoprotein comprising a protein moiety that comprises the amino acid sequence of Major Royal Jelly Protein 1 (MRJP1), the MRJP1 sequence comprising the amino acid sequence TPFKISIHL in the C-terminal region, and at least two carbohydrate moieties, wherein two or more of the at least two carbohydrate moieties each comprise a mannosylated glycan. The composition may be formulated for topical administration and/or may be included in a wound dressing. Also provided are methods and uses relating to use of the composition or wound dressing for treating a wound, including treatment to prevent or reduce infection or contamination with multidrug resistant bacteria.